Effect of Javanese Ginseng (Talinum Paniculatum (Jacq.) Gaertn) Leaf Extract on Spermatozoa Quality of Mice (Mus Musculus)


July 28, 2023


Java Ginseng (Talinum paniculatum (Jacq.) Gaertn) or commonly known as som jawa is one of the local plants in Java. Pharmacological studies have proven its potential as an antidiabetic, antinociceptive, antimicrobial, antioxidant and to treat digestive disorders. Research on Javanese Ginseng leaves proves its benefits on improving mating behavior and increasing libido of male rats, while its roots are proven to improve the quality of mice spermatozoa, but there has been no further research on the effect of Javanese ginseng leaf on the quality of mice spermatozoa. This study aims to determine the effect of Javanese ginseng leaf extract on testicular weight and spermatozoa quality of mice. The design used was a one-factor RBD with 4 treatments, namely the control group (P0) which was only given food and drink, group P1 was given a dose of T. paniculatum (Jacq.) Gaertn leaf extract in a number of doses of 0,98mg/20g, 2,8mg/20g, 7,7mg/20g. Each treatment consisted of 5 replicates. The parameters observed were testicular weight, amount, motility, viability, morphology of male mice cauda epididymis spermatozoa. Giving ethanol extract of T. paniculatum (Jacq.) Gaertn leaves to mice by gavage for 16 days. The observational data were analyzed with ANOVA (Analysis of Variance) and continued with Duncan’s test at a level of 5%. Based on the results of the study that have been analyzed using one way ANOVA, it shows that ginseng leaf extract increases testicular weight, type A motility, viability and amount of spermatozoa, but morphology between control and treatment groups (P1, P2, P3) are not significantly different (p>0,05). The most effective dose of T.  paniculatum leaf extract was 7,7mg/20mg (treatment P3) which showed the best results in the parameters and was significantly different from treatment P0 (control).


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